Maternal prenatal smoking and offspring emotional problems: no moderating effect of maternal or child 5-HTTLPR genotype.

نویسندگان

  • Lot M Geels
  • Maria M Groen-Blokhuis
  • Catharina E M van Beijsterveldt
  • Jacqueline M Vink
  • Christel M Middeldorp
  • Meike Bartels
  • Kelly A Nelson
  • Patricia E Huizenga
  • Gareth E Davies
  • Dorret I Boomsma
چکیده

Maternal Prenatal Smoking and Offspring Emotional Problems: No Moderating Effect of Maternal or Child 5-HTTLPR Genotype Lot M. Geels,* Maria M. Groen-Blokhuis, Catharina E.M. van Beijsterveldt, Jacqueline M. Vink, Christel M. Middeldorp, Meike Bartels, Kelly A. Nelson, Patricia E. Huizenga, Gareth E. Davies, and Dorret I. Boomsma Department of Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands EMGOþ Institute for Health and Care Research, VU University Medical Center Amsterdam, Amsterdam, The Netherlands Neuroscience Campus Amsterdam, Amsterdam, The Netherlands Department of Child and Adolescent Psychiatry, GGZ in Geest/VU Medical Center, Amsterdam, The Netherlands Avera Institute for Human Genetics, Avera Behavioral Center, Sioux Falls, South Dakota

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

No Moderating Effect of 5-HTTLPR on Associations Between Antenatal Anxiety and Infant Behavior

OBJECTIVE Maternal antenatal anxiety is associated with an increased risk of behavioral disturbances in offspring. Recent work has suggested that the effect of maternal antenatal anxiety on infant temperament at 6 months is moderated by the serotonin transporter polymorphism 5-HTTLPR, with carriers of the short allele more susceptible to the adverse behavioral outcomes of maternal antenatal anx...

متن کامل

Maternal smoking and child psychological problems: disentangling causal and noncausal effects.

OBJECTIVE To explore associations of maternal prenatal smoking and child psychological problems and determine the role of causal intrauterine mechanisms. PATIENTS AND METHODS Maternal smoking and child psychological problems were explored in 2 birth cohorts in Pelotas, Brazil (n = 509, random subsample), and the Avon Longitudinal Study of Parents and Children (ALSPAC) in Britain (n = 6735). F...

متن کامل

Maternal folate status in early pregnancy and child emotional and behavioral problems: the Generation R Study.

BACKGROUND Maternal prenatal folate status has been linked to neurodevelopmental disorders, but the association with child emotional and behavioral problems is unclear. OBJECTIVES We assessed the association of maternal folate status during pregnancy with child emotional and behavioral problems. Also, we examined whether any association between folate status and child problems is a consequenc...

متن کامل

Effects of Genotype and Sleep on Temperament.

BACKGROUND AND OBJECTIVES Sleep problems are frequent in young children; however, children vary in the degree to which they are affected by poor sleep quality. We investigated whether a polymorphism in the serotonin transporter gene, which is linked to emotional function, is a potential moderator of the influences of sleep duration on infant temperament using longitudinal data. METHODS We exa...

متن کامل

A Challenging Issue in the Etiology of Speech Problems: The Effect of Maternal Exposure to Electromagnetic Fields on Speech Problems in the Offspring

Background: Nowadays, mothers are continuously exposed to different sources of electromagnetic fields before and even during pregnancy.  It has recently been shown that exposure to mobile phone radiation during pregnancy may lead to adverse effects on the brain development in offspring and cause hyperactivity. Researchers have shown that behavioral problems in laboratory animals which have a s...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics

دوره 159B 8  شماره 

صفحات  -

تاریخ انتشار 2012